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Article de santé publique

Effects of exercise on high-density lipoprotein levels in middle-aged and older individuals: A systematic review and meta-analysis



Examiner l'évaluation de la qualité : 9 (strong)

Référence: Liang L, Peng F, Wang L, Lin C, & Chi H. (2025). Effects of exercise on high-density lipoprotein levels in middle-aged and older individuals: A systematic review and meta-analysis. Medicine, 104(6).

Résumé des données probantes Lien vers PubMed

Résumé (en anglais)

BACKGROUND: This study aimed to perform a systematic review and meta-analysis of randomized controlled trials investigating the effect of exercise on high-density lipoprotein (HDL) levels in middle-aged and older individuals.

METHODS: A systematic search was conducted in PubMed, Web of Science, and EMBASE, including meta-analyses of randomized controlled trials that investigated the effects of exercise on HDL-C levels in middle-aged and older individuals.

RESULTS: Forty-two trials were analyzed. We found that exercise had a significant effect on HDL cholesterol levels (standard mean difference [95% confidence interval] = 0.22 [0.09-0.35], Z = 3.28, P = .001, I2 = 54%), and the heterogeneity across the studies was significant and high. After subgroup analysis, we found that aerobic exercise had the most significant effect on the levels of HDLs in middle-aged and older individuals, which was better than that of other types of exercise.

CONCLUSIONS: Aerobic exercise significantly improves HDL levels in middle-aged and older individuals, but resistance and stretching exercises had no significant effect on HDL levels.


Mots-clés

activité physique, Adultes, Alimentation et nutrition, domicile, fournisseur de soins de santé primaires, la santé à travers les ages , Maladie chronique, maladies cardiovasculaires, méta-analyse, milieu de soins de santé, Modification du comportement, Personnes âgées, revue narrative, santé des aînés

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